Dihydroberberine

Dihydroberberine

Dihydroberberine

CAS No.: 483-15-8

MOQ: 200KG

Dihydroberberine (HPLC) is a hydrogenated derivative of berberine, a bioactive alkaloid found in plants like Berberis vulgaris (barberry), Coptis chinensis, and Hydrastis canadensis (goldenseal). It is formed by reducing berberine’s double bonds, which enhances its bioavailability and metabolic stability.

Chempora is a leading supplier of Dihydroberberine (DHB) , we provide customers with high quality Dihydroberberine, if you have any requirements, please feel free to contact [email protected], we will reply you as soon as possible.

Specification Available: USP

Product Introduction of Dihydroberberine

Dihydroberberine (DHB) is a hydrogenated derivative of berberine, a bioactive alkaloid found in plants like goldenseal, barberry, and Chinese goldthread. It is known for its potential enhanced bioavailability compared to regular berberine, which is poorly absorbed in the gut.

Dihydroberberine
Dihydroberberine

Dihydroberberine Basic Information

  • Chemical Formula: C20H19NO4 
  • Chemical Name: 5,6-Dihydroberberine
  • Molecular Weight: 337.37 g/mol 2
  • Purity: 98%
  • Appearance: light yellow to white crystalline powder
  • Solubility: slightly soluble in water, easily soluble in organic solvents (such as DMSO, ethanol)
  • Stability: avoid light and moisture, it is recommended to store in a cool and dry place (2-8°C is best)

Key Benefits of Dihydroberberine

1. Blood Sugar Regulation

Dihydroberberine has been shown to effectively improve insulin sensitivity, support healthy blood sugar levels, and enhance glucose metabolism. It is considered more potent than berberine in its ability to manage blood sugar, making it a promising supplement for individuals with insulin resistance or type 2 diabetes.

2. Enhanced Fat Metabolism

This compound has demonstrated the ability to modulate lipid metabolism, which may help in reducing body fat and managing cholesterol levels, contributing to better heart health and weight management.

3. Anti-Inflammatory and Antioxidant Effects

Dihydroberberine provides strong anti-inflammatory benefits, which can help reduce chronic inflammation associated with various metabolic disorders. Additionally, its antioxidant properties aid in neutralizing harmful free radicals, supporting overall cellular health and slowing the aging process.

4. Improved Bioavailability

Compared to regular berberine, Dihydroberberine offers enhanced absorption and longer-lasting effects, making it a more effective choice for therapeutic purposes.

Product Parameter of Dihydroberberine

Items Specifications Test Results Methods
Specifications
Purity of Dihydroberberine NLT 98.0 % 99.30 % HPLC
Assay of Dihydroberberine NLT 98.0 % 99.52% HPLC
Physical & Chemical Control:
Appearance Yellow powder Conforms Organoleptic
Odor & Taste Characteristic Conforms Organoleptic
Identification HPLC retention time correspond to Reference Standard Conforms In house HPLC
Particle size NLT 90% pass 40 mesh Conforms USP <786>
Water NMT 1.0 % 0.19% USP <921>
Residue on ignition NMT 1.0 % 0.05 % USP <281>
Bulk density (loose) NLT 0.5 g/ml 0.63 g/ml USP <616>
Bulk density (tapped) NLT 0.7 g/ml 0.84 g/ml USP <616>
Residual solvents Under USP <467> limits Conforms USP <467>
Residual pesticides Under USP <565> limits Conforms USP <565>
Heavy Metals Control:
Heavy Metals NMT 10 mg/kg Conforms USP <233>
Lead NMT 2.0 mg/kg 0.152 mg/kg USP <233>
Arsenic NMT 2.0 mg/kg 0.018 mg/kg USP <233>
Cadmium NMT 1.0 mg/kg ND USP <233>
Mercury NMT 1.0 mg/kg ND USP <233>
Microbiological Control:
Total Plate Count NMT 1,000 cfu/g <10 cfu/g USP <61>
Yeast & Mold NMT 100 cfu/g <10 cfu/g USP <61>
E. Coli Negative Conforms USP <62>
Salmonella Negative Conforms USP <62>
S. Aureus Negative Conforms USP <62>
Packing: Pack in fiber-drums double and plastic-bags inside. Net weight 20kg/drum.
Storage: Sealed and stored in cool and dry place, protect from direct sunlight and moisture.

Why choose to buy Chempora of Dihydroberberine?

Chempora is a trusted trading company specializing in high-quality ingredients and raw materials for various industries, including nutritional supplements, food additives, feed additives, and herbal extracts. They focus on providing top-notch products, reliable supply chains, and professional support, which makes them a reliable partner for businesses worldwide.

When choosing to buy Chempora’s Dihydroberberine, you can expect:

1. High Quality : They offer Dihydroberberine that meets stringent quality control standards.

2. Reliable Supply Chain: Ensuring timely deliveries and consistent product availability.

3. Competitive Pricing: Offering competitive rates without compromising quality.

4. Professional Support: Expert advice and tailored solutions to meet specific customer needs.

This makes Chempora a solid choice if you’re looking for high purity and dependable Dihydroberberine products.

Contact Us

CHEMPORA CO., LIMITED

Contact Person: Mr. Stephen Ding

Tel:0086-21-58930128

WhatsApp & Wechat: +8615026665594

E-mail: [email protected]

Contact with CHEMPORA

Application of Dihydroberberine

Dihydroberberine (HPLC) can be used in a variety of products, primarily in health and wellness sectors:

1. Dietary Supplements

Dihydroberberine is commonly used in supplements for blood sugar management, weight loss, heart health, and general metabolic support due to its effects on glucose regulation and fat metabolism.

2. Functional Foods

It can be added to low-sugar or low-carb foods to help manage blood sugar levels and promote fat burning.

3. Skincare Products

Dihydroberberine’s antioxidant and anti-inflammatory properties make it useful in anti-aging and skin-soothing formulations.

4. Sports Nutrition

Dihydroberberine is found in supplements that support fat burning, energy metabolism, and improved athletic performance.

5. Metabolic Support Products

Used in products designed to support overall metabolic health, especially for managing conditions like metabolic syndrome.

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Berberine HCl Powder holds significant application value across multiple industries. Its natural, effective, and multifunctional properties make it an ideal raw material for use in food, pharmaceuticals, healthcare, and scientific research fields. For more information, please feel free to contact us !

Differences between Dihydroberberine and Berberine HCL Powder

Dihydroberberine and Berberine HCL Powder are both derived from the same plant family, but they have distinct differences in terms of their chemical structure, bioavailability, and potential health benefits. Here’s a breakdown of the key differences:

Property Dihydroberberine (DHB) Berberine HCL Powder
Bioavailability Higher bioavailability, absorbed more efficiently in the body Lower bioavailability, requires higher doses for similar effects
Effectiveness More potent in lowering blood glucose and improving insulin sensitivity Effective, but generally less potent than DHB in comparison
Metabolism Faster and more easily metabolized due to better absorption Slower metabolism with potential for more gastrointestinal discomfort
Side Effects Fewer gastrointestinal side effects due to better absorption May cause digestive issues like nausea or upset stomach
Applications Used in dietary supplements for better blood sugar control, fat loss, and cardiovascular health Widely used for managing blood sugar, cholesterol, and metabolic health
Cost More expensive due to enhanced bioavailability and production process Generally less expensive, but requires higher dosage for similar benefits

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